Singanitropin is a brand of recombinant human growth hormone (rHGH) marketed by a Chinese pharmaceutical company called Singani Pharma. This medication is used to treat growth hormone deficiency (GHD) in adults and children. Singanitropin is a prescription-only medication that comes in the form of a lyophilized powder that needs to be mixed with sterile water before administration.

Indication:

Singanitropin is used to treat individuals with GHD, which is a medical condition characterized by a shortage of natural growth hormone in the body. GHD can lead to a variety of symptoms, such as stunted growth, low energy levels, and a decrease in muscle mass and bone density.

Mechanism of Action:

The active ingredient in Singanitropin is somatropin, which is a synthetic version of the human growth hormone. Somatropin stimulates the liver and other tissues to produce insulin-like growth factor-1 (IGF-1). IGF-1 is one of the key regulators of cell growth and division. By increasing IGF-1 levels in the body, somatropin promotes growth and development in children with GHD, while also promoting muscle growth, bone density, and energy levels in adults.

Administration and Dosage:

Singanitropin is administered through injection. The dosage will depend on the patient’s age, weight, medical history, and condition being treated. In children with GHD, the initial dose may be around 0.025 mg/kg body weight per day, with the dose adjusted over time as necessary. Adults with GHD generally take 0.2 to 0.5 mg per day, given as one daily injection. It is important to follow the prescribing doctor’s instructions for dosing and administration carefully.

Efficacy:

Studies have demonstrated that Singanitropin is effective in treating GHD in both children and adults. The medication has been shown to increase height and growth velocity in children with GHD, while also increasing bone density, muscle mass, and energy levels in adults.

Side Effects:

Like all medications, Singanitropin can cause side effects. Common side effects may include swelling, redness, and pain at the injection site, nausea, vomiting, headache, itching, and joint pain. Serious side effects are rare, but can include increased intracranial pressure, worsening of pre-existing scoliosis, and an increased risk of developing diabetes.

Precautions:

Before using Singanitropin, patients should inform their doctor of any other medical conditions and medications they are taking. Patients with a history of cancer, breathing problems, or other medical conditions that may be affected by the drug should avoid using it. Patients with diabetes should be monitored closely during treatment as the drug may affect glucose levels in the blood. Patients who are pregnant or breastfeeding or trying to conceive should not use Singanitropin.